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Alpha 1-antitrypsin deficiency, complement activation, and chronic liver disease.

Activation of the complement system, the main humoral mediator of inflammation, is restrained by the action of enzyme inhibitors including alpha 1-antitrypsin. Deficiency leads to chronic liver disease in about one in five children with this genetic defect. Complement activation was investigated in...

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Bibliografski detalji
Glavni autori: Littleton, E T, Bevis, L, Hansen, L J, Peakman, M, Mowat, A P, Mieli-Vergani, G, Vergani, D
Format: Artigo
Jezik:Inglês
Izdano: 1991
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC496674/
https://ncbi.nlm.nih.gov/pubmed/1960220
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