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Epidermal CYLD inactivation sensitizes mice to the development of sebaceous and basaloid skin tumors
The deubiquitinase-encoding gene Cyld displays a dominant genetic linkage to a wide spectrum of skin-appendage tumors, which could be collectively designated as CYLD mutant–syndrome (CYLD(m)-syndrome). Despite recent advances, little is understood about the molecular mechanisms responsible for this...
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| Pubblicato in: | JCI Insight |
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| Autori principali: | , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
American Society for Clinical Investigation
2016
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4966682/ https://ncbi.nlm.nih.gov/pubmed/27478875 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.86548 |
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