Discovery and characterization of COVA322, a clinical-stage bispecific TNF/IL-17A inhibitor for the treatment of inflammatory diseases

Biologic treatment options such as tumor necrosis factor (TNF) inhibitors have revolutionized the treatment of inflammatory diseases, including rheumatoid arthritis. Recent data suggest, however, that full and long-lasting responses to TNF inhibitors are limited because of the activation of the pro-...

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Detalhes bibliográficos
Publicado no:MAbs
Main Authors: Silacci, Michela, Lembke, Wibke, Woods, Richard, Attinger-Toller, Isabella, Baenziger-Tobler, Nadja, Batey, Sarah, Santimaria, Roger, von der Bey, Ulrike, Koenig-Friedrich, Susann, Zha, Wenjuan, Schlereth, Bernd, Locher, Mathias, Bertschinger, Julian, Grabulovski, Dragan
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2015
Assuntos:
Report
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4966518/
https://ncbi.nlm.nih.gov/pubmed/26390837
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/19420862.2015.1093266
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