Rapid quantitative analysis of monoclonal antibody heavy and light chain charge heterogeneity

An alternative method to traditional 2-dimensional gel electrophoresis (2D-PAGE) and its application in characterizing the inherent charge heterogeneity of chromatographically isolated monoclonal antibody heavy and light chains is described. This method, referred to as ChromiCE, utilizes analytical...

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Bibliografische gegevens
Gepubliceerd in:MAbs
Hoofdauteurs: Vanam, Ram P, Schneider, Michael A, Marlow, Michael S
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Taylor & Francis 2015
Onderwerpen:
Report
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4966340/
https://ncbi.nlm.nih.gov/pubmed/26305772
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/19420862.2015.1085145
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