Induced superficial chondrocyte death reduces catabolic cartilage damage in murine posttraumatic osteoarthritis

Joints that have degenerated as a result of aging or injury contain dead chondrocytes and damaged cartilage. Some studies have suggested that chondrocyte death precedes cartilage damage, but how the loss of chondrocytes affects cartilage integrity is not clear. In this study, we examined whether cho...

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Detalhes bibliográficos
Publicado no:J Clin Invest
Main Authors: Zhang, Minjie, Mani, Sriniwasan B., He, Yao, Hall, Amber M., Xu, Lin, Li, Yefu, Zurakowski, David, Jay, Gregory D., Warman, Matthew L.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2016
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4966316/
https://ncbi.nlm.nih.gov/pubmed/27427985
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI83676
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