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Methadone Reverses Analgesic Tolerance Induced by Morphine Pretreatment

BACKGROUND: Opiates such as morphine are the most powerful analgesics, but their protracted use is restrained by the development of tolerance to analgesic effects. Recent works suggest that tolerance to morphine might be due to its inability to promote mu opioid receptor endocytosis, and the co-inje...

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Kaydedildi:
Detaylı Bibliyografya
Yayımlandı:Int J Neuropsychopharmacol
Asıl Yazarlar: Posa, Luca, Accarie, Alison, Noble, Florence, Marie, Nicolas
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Oxford University Press 2015
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4966270/
https://ncbi.nlm.nih.gov/pubmed/26390873
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/ijnp/pyv108
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