Role of Keap1-Nrf2 signaling in depression and dietary intake of glucoraphanin confers stress resilience in mice

The transcription factor Keap1-Nrf2 system plays a key role in inflammation which is involved in depression. We found lower expression of Keap1 and Nrf2 proteins in the prefrontal cortex (PFC), CA3 and dentate gyrus (DG) of hippocampus in mice with depression-like phenotype compared to control mice....

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Vydáno v:Sci Rep
Hlavní autoři: Yao, Wei, Zhang, Ji-chun, Ishima, Tamaki, Dong, Chao, Yang, Chun, Ren, Qian, Ma, Min, Han, Mei, Wu, Jin, Suganuma, Hiroyuki, Ushida, Yusuke, Yamamoto, Masayuki, Hashimoto, Kenji
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 2016
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4965765/
https://ncbi.nlm.nih.gov/pubmed/27470577
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep30659
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