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Fibroblast growth factor 21 reflects liver fat accumulation and dysregulation of signalling pathways in the liver of C57BL/6J mice

Fibroblast growth factor 21 (Fgf21) has emerged as a potential plasma marker to diagnose non-alcoholic fatty liver disease (NAFLD). To study the molecular processes underlying the association of plasma Fgf21 with NAFLD, we explored the liver transcriptome data of a mild NAFLD model of aging C57BL/6J...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Rusli, Fenni, Deelen, Joris, Andriyani, Evi, Boekschoten, Mark V., Lute, Carolien, van den Akker, Erik B., Müller, Michael, Beekman, Marian, Steegenga, Wilma T
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4965761/
https://ncbi.nlm.nih.gov/pubmed/27470139
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep30484
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