Folate-Chitosan Nanoparticles Loaded with Ursolic Acid Confer Anti-Breast Cancer Activities in vitro and in vivo

Ursolic acid (UA) has proved to have broad-spectrum anti-tumor effects, but its poor water solubility and incompetent targeting property largely limit its clinical application and efficiency. Here, we synthesized a nanoparticle-based drug carrier composed of chitosan, UA and folate (FA-CS-UA-NPs) an...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Jin, Hua, Pi, Jiang, Yang, Fen, Jiang, Jinhuan, Wang, Xiaoping, Bai, Haihua, Shao, Mingtao, Huang, Lei, Zhu, Haiyan, Yang, Peihui, Li, Lihua, Li, Ting, Cai, Jiye, Chen, Zheng W.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4965748/
https://ncbi.nlm.nih.gov/pubmed/27469490
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep30782
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