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OxyR2 Functions as a Three-state Redox Switch to Tightly Regulate Production of Prx2, a Peroxiredoxin of Vibrio vulnificus

The bacterial transcriptional regulator OxyR is known to function as a two-state redox switch. OxyR senses cellular levels of H(2)O(2) via a “sensing cysteine” that switches from the reduced to a disulfide state upon H(2)O(2) exposure, inducing the expression of antioxidant genes. The reduced and di...

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Foilsithe in:J Biol Chem
Main Authors: Bang, Ye-Ji, Lee, Zee-Won, Kim, Dukyun, Jo, Inseong, Ha, Nam-Chul, Choi, Sang Ho
Formáid: Artigo
Teanga:Inglês
Foilsithe: American Society for Biochemistry and Molecular Biology 2016
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4965554/
https://ncbi.nlm.nih.gov/pubmed/27268058
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.710343
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