Electroresponsive Nanoparticles Improve Antiseizure Effect of Phenytoin in Generalized Tonic-Clonic Seizures

Previously, we developed electroresponsive hydrogel nanoparticles (ERHNPs) modified with angiopep-2 (ANG) to facilitate the delivery of the antiseizure drug phenytoin sodium (PHT). However, the electroresponsive characteristics were not verified directly in epileptic mice and the optimal preparation...

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Detalhes bibliográficos
Publicado no:Neurotherapeutics
Principais autores: Wang, Yi, Ying, Xiaoying, Chen, Liying, Liu, Yao, Wang, Ying, Liang, Jiao, Xu, Cenglin, Guo, Yi, Wang, Shuang, Hu, Weiwei, Du, Yongzhong, Chen, Zhong
Formato: Artigo
Idioma:Inglês
Publicado em: Springer US 2016
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4965401/
https://ncbi.nlm.nih.gov/pubmed/27137202
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s13311-016-0431-9
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