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Power/Sample Size Calculations for Assessing Correlates of Risk in Clinical Efficacy Trials

In a randomized controlled clinical trial that assesses treatment efficacy, a common objective is to assess the association of a measured biomarker response endpoint with the primary study endpoint in the active treatment group, using a case-cohort, case-control, or two-phase sampling design. Method...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Stat Med
Hauptverfasser: Gilbert, Peter B., Janes, Holly E., Huang, Yunda
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2016
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4965346/
https://ncbi.nlm.nih.gov/pubmed/27037797
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/sim.6952
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