Familial adenomatous patients with desmoid tumours show increased expression of miR-34a in serum and high levels in tumours

Familial adenomatous polyposis (FAP) is rare affecting 1 in 10,000 people and a subset (10%) are at risk of myofibroblastic desmoid tumours (DTs) after colectomy to prevent cancer. DTs are a major cause of morbidity and mortality. The absence of markers to monitor progression and a lack of treatment...

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Udgivet i:Oncoscience
Main Authors: Walton, Sarah-Jane, Lewis, Amy, Jeffery, Rosemary, Thompson, Hannah, Feakins, Roger, Giannoulatou, Eleni, Yau, Christopher, Lindsay, James O., Clark, Susan K., Silver, Andrew
Format: Artigo
Sprog:Inglês
Udgivet: Impact Journals LLC 2016
Fag:
Research Paper
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4965260/
https://ncbi.nlm.nih.gov/pubmed/27489864
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncoscience.312
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