Up-Regulation of CYP2C19 Expression by BuChang NaoXinTong via PXR Activation in HepG2 Cells

BACKGROUND: Cytochrome P450 2C19 (CYP2C19) is an important drug-metabolizing enzyme (DME), which is responsible for the biotransformation of several kinds of drugs such as proton pump inhibitors, platelet aggregation inhibitors and antidepressants. Previous studies showed that Buchang NaoXinTong cap...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Sun, Hong, Lou, Xiao-Ya, Wu, Xiao-Ying, Wang, Huan, Qu, Qiang, Tan, Shen-Lan, Ruan, Jun-Shan, Qu, Jian, Chen, Hui
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2016
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4965156/
https://ncbi.nlm.nih.gov/pubmed/27467078
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0160285
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