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Up-Regulation of CYP2C19 Expression by BuChang NaoXinTong via PXR Activation in HepG2 Cells

BACKGROUND: Cytochrome P450 2C19 (CYP2C19) is an important drug-metabolizing enzyme (DME), which is responsible for the biotransformation of several kinds of drugs such as proton pump inhibitors, platelet aggregation inhibitors and antidepressants. Previous studies showed that Buchang NaoXinTong cap...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
הוצא לאור ב:PLoS One
Main Authors: Sun, Hong, Lou, Xiao-Ya, Wu, Xiao-Ying, Wang, Huan, Qu, Qiang, Tan, Shen-Lan, Ruan, Jun-Shan, Qu, Jian, Chen, Hui
פורמט: Artigo
שפה:Inglês
יצא לאור: Public Library of Science 2016
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC4965156/
https://ncbi.nlm.nih.gov/pubmed/27467078
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0160285
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