Targeting Tumor Necrosis Factor-α with Adalimumab: Effects on Endothelial Activation and Monocyte Adhesion

OBJECTIVE: It is well known that atherosclerotic inflammatory vascular disease is critically driven by oxidized lipids and cytokines. In this regard, tumor necrosis factor (TNF)-α is known as a crucial mediator of early pro-atherosclerotic events. Epidemiologic data suggest that blockade of TNF-α ha...

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Udgivet i:PLoS One
Main Authors: Oberoi, Raghav, Schuett, Jutta, Schuett, Harald, Koch, Ann-Kathrin, Luchtefeld, Maren, Grote, Karsten, Schieffer, Bernhard
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2016
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4965117/
https://ncbi.nlm.nih.gov/pubmed/27467817
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0160145
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