B-Cell Dysregulation in Crohn's Disease Is Partially Restored with Infliximab Therapy

BACKGROUND: B-cell depletion can improve a variety of chronic inflammatory diseases, but does not appear beneficial for patients with Crohn’s disease. OBJECTIVE: To elucidate the involvement of B cells in Crohn’s disease, we here performed an ‘in depth’ analysis of intestinal and blood B-cells in th...

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發表在:PLoS One
Main Authors: Timmermans, Wilhelmina M. C., van Laar, Jan A. M., van der Houwen, Tim B., Kamphuis, Lieke S. J., Bartol, Sophinus J. W., Lam, King H., Ouwendijk, Rob J., Sparrow, Miles P., Gibson, Peter R., van Hagen, P. Martin, van Zelm, Menno C.
格式: Artigo
語言:Inglês
出版: Public Library of Science 2016
主題:
Research Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4965034/
https://ncbi.nlm.nih.gov/pubmed/27468085
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0160103
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