B-Cell Dysregulation in Crohn's Disease Is Partially Restored with Infliximab Therapy

BACKGROUND: B-cell depletion can improve a variety of chronic inflammatory diseases, but does not appear beneficial for patients with Crohn’s disease. OBJECTIVE: To elucidate the involvement of B cells in Crohn’s disease, we here performed an ‘in depth’ analysis of intestinal and blood B-cells in th...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Timmermans, Wilhelmina M. C., van Laar, Jan A. M., van der Houwen, Tim B., Kamphuis, Lieke S. J., Bartol, Sophinus J. W., Lam, King H., Ouwendijk, Rob J., Sparrow, Miles P., Gibson, Peter R., van Hagen, P. Martin, van Zelm, Menno C.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2016
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4965034/
https://ncbi.nlm.nih.gov/pubmed/27468085
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0160103
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