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Protein misfolding in Dictyostelium: Using a freak of nature to gain insight into a universal problem

Prion-like proteins can undergo conformational rearrangements from an intrinsically disordered to a highly ordered amyloid state. This ability to change conformation is encoded in distinctive domains, termed prion domains (PrDs). Previous work suggests that PrDs change conformation to affect protein...

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Dades bibliogràfiques
Publicat a:Prion
Autors principals: Malinovska, Liliana, Alberti, Simon
Format: Artigo
Idioma:Inglês
Publicat: Taylor & Francis 2015
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4964863/
https://ncbi.nlm.nih.gov/pubmed/26529309
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/19336896.2015.1099799
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