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Mass spectrometric immunoassays for discovery, screening and quantification of clinically relevant proteoforms

Human proteins can exist as multiple proteoforms with potential diagnostic or prognostic significance. MS top-down approaches are ideally suited for proteoforms identification because there is no prerequisite for a priori knowledge of the specific proteoform. One such top-down approach, termed mass...

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Detalhes bibliográficos
Publicado no:Bioanalysis
Main Authors: Trenchevska, Olgica, Nelson, Randall W, Nedelkov, Dobrin
Formato: Artigo
Idioma:Inglês
Publicado em: Future Science Ltd 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4964736/
https://ncbi.nlm.nih.gov/pubmed/27396364
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4155/bio-2016-0060
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