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Allele-specific locus binding and genome editing by CRISPR at the p16INK4a locus

The clustered regularly interspaced short palindromic repeats (CRISPR) system has been adopted for a wide range of biological applications including genome editing. In some cases, dissection of genome functions requires allele-specific genome editing, but the use of CRISPR for this purpose has not b...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Sci Rep
Main Authors: Fujita, Toshitsugu, Yuno, Miyuki, Fujii, Hodaka
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group 2016
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4964623/
https://ncbi.nlm.nih.gov/pubmed/27465215
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep30485
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