Integrating Epigenomic Elements and GWASs Identifies BDNF Gene Affecting Bone Mineral Density and Osteoporotic Fracture Risk

To identify susceptibility genes for osteoporosis, we conducted an integrative analysis that combined epigenomic elements and previous genome-wide association studies (GWASs) data, followed by validation at population and functional levels, which could identify common regulatory elements and predict...

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Publicat a:Sci Rep
Autors principals: Guo, Yan, Dong, Shan-Shan, Chen, Xiao-Feng, Jing, Ying-Aisha, Yang, Man, Yan, Han, Shen, Hui, Chen, Xiang-Ding, Tan, Li-Jun, Tian, Qing, Deng, Hong-Wen, Yang, Tie-Lin
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2016
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4964617/
https://ncbi.nlm.nih.gov/pubmed/27465306
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep30558
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