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Senescence in Human Mesenchymal Stem Cells: Functional Changes and Implications in Stem Cell-Based Therapy

Regenerative medicine is extensively interested in developing cell therapies using mesenchymal stem cells (MSCs), with applications to several aging-associated diseases. For successful therapies, a substantial number of cells are needed, requiring extensive ex vivo cell expansion. However, MSC proli...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Turinetto, Valentina, Vitale, Emanuela, Giachino, Claudia
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4964536/
https://ncbi.nlm.nih.gov/pubmed/27447618
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms17071164
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