Human Aquaporin-4 and Molecular Modeling: Historical Perspective and View to the Future

Among the different aquaporins (AQPs), human aquaporin-4 (hAQP4) has attracted the greatest interest in recent years as a new promising therapeutic target. Such a membrane protein is, in fact, involved in a multiple sclerosis-like immunopathology called Neuromyelitis Optica (NMO) and in several diso...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Int J Mol Sci
Hauptverfasser: Mangiatordi, Giuseppe Felice, Alberga, Domenico, Trisciuzzi, Daniela, Lattanzi, Gianluca, Nicolotti, Orazio
Format: Artigo
Sprache:Inglês
Veröffentlicht: MDPI 2016
Schlagworte:
Review
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4964494/
https://ncbi.nlm.nih.gov/pubmed/27420052
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms17071119
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