Poly(ADP-ribose) polymerase inhibition suppresses inflammation and promotes recovery from adrenal injury in a rat model of acute necrotizing pancreatitis

BACKGROUND: Poly(ADP-ribose) polymerase (PARP) participates in multi-organ failure in various inflammatory diseases including acute necrotizing pancreatitis (ANP). Since pancreatitis-associated adrenal insufficiency is partly caused by inflammatory damage to the adrenal cortex, we examined whether P...

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Pubblicato in:BMC Gastroenterol
Autori principali: Yu, Jia, Zuo, Teng, Deng, Wenhong, Shi, Qiao, Ma, Peng, Chen, Chen, Zhao, Liang, Zhao, Kailiang, Wang, Weixing
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2016
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4964309/
https://ncbi.nlm.nih.gov/pubmed/27465581
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12876-016-0493-5
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