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Invasiveness of pharmacokinetic studies in children: a systematic review

OBJECTIVES: To explore whether pharmacokinetic (PK) studies in paediatric patients are becoming less invasive. This will be evaluated by analysing the number of samples and volume of blood collected for each study within four different decades. METHODS: A systematic literature review was performed t...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:BMJ Open
Hauptverfasser: Altamimi, Mohammed I, Choonara, Imti, Sammons, Helen
Format: Artigo
Sprache:Inglês
Veröffentlicht: BMJ Publishing Group 2016
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4964204/
https://ncbi.nlm.nih.gov/pubmed/27431899
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/bmjopen-2015-010484
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