High EZH2 expression is correlated to metastatic disease in pediatric soft tissue sarcomas

BACKGROUND: Enhancer of Zeste Drosophila Homologue 2 (EZH2) is a key regulator of transcription as a member of polycomb repressive complex 2 (PRC2) which exerts repression of downstream genes and is correlated to invasiveness and progression of different tumours. Therefore, we evaluated the expressi...

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Detalhes bibliográficos
Publicado no:Cancer Cell Int
Main Authors: Ramaglia, Maria, D’Angelo, Velia, Iannotta, Adriana, Di Pinto, Daniela, Pota, Elvira, Affinita, Maria Carmen, Donofrio, Vittoria, Errico, Maria Elena, Lombardi, Angela, Indolfi, Cristiana, Casale, Fiorina, Caraglia, Michele
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2016
Assuntos:
Primary Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4964052/
https://ncbi.nlm.nih.gov/pubmed/27471434
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12935-016-0338-x
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