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Short telomere length and its correlation with gene mutations in myelodysplastic syndrome

BACKGROUND: Telomere erosion can lead to genomic instability and cancer progression. It has been suggested that the shortest telomere, not the average telomere length (TL), is critical for cell viability. Some studies have shown shorter TL in myelodysplastic syndrome (MDS) patients but the criticall...

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Detalhes bibliográficos
Publicado no:J Hematol Oncol
Main Authors: Hwang, Sang Mee, Kim, Seon Young, Kim, Jung Ah, Park, Hee-Sue, Park, Si Nae, Im, Kyongok, Kim, Kwantae, Kim, Sung-Min, Lee, Dong Soon
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4964031/
https://ncbi.nlm.nih.gov/pubmed/27465399
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13045-016-0287-9
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