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Modulating Dickkopf-1: A Strategy to Monitor or Treat Cancer?

Dickkopf-1 (DKK1) is a secreted Wnt/β-catenin pathway antagonist involved in embryogenesis. It was first described 25 years ago for its function in head induction and limb morphogenesis. Since then, this protein has been widely studied in the context of active Wnt/β-catenin signalling during cellula...

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Detalhes bibliográficos
Publicado no:Cancers (Basel)
Main Authors: Mazon, Mélody, Masi, Delphine, Carreau, Madeleine
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4963804/
https://ncbi.nlm.nih.gov/pubmed/27367730
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers8070062
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