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Saccharomyces cerevisiae sec59 cells are deficient in dolichol kinase activity.

The temperature-sensitive Saccharomyces cerevisiae mutant sec59 accumulates inactive and incompletely glycosylated protein precursors in its endoplasmic reticulum at the restrictive temperature. O-mannosylation and glycosyl phosphatidylinositol membrane anchoring of protein are also abolished, consi...

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Bibliographic Details
Main Authors: Heller, L, Orlean, P, Adair, W L
Format: Artigo
Language:Inglês
Published: 1992
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC49635/
https://ncbi.nlm.nih.gov/pubmed/1323123
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