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The Mediator complex: a central integrator of transcription
The RNA polymerase II (pol II) enzyme transcribes all protein-coding and most non-coding RNA genes and is globally regulated by Mediator, a large, conformationally flexible protein complex with variable subunit composition (for example, a four-subunit CDK8 module can reversibly associate). These bio...
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| Veröffentlicht in: | Nat Rev Mol Cell Biol |
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| Hauptverfasser: | , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2015
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4963239/ https://ncbi.nlm.nih.gov/pubmed/25693131 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nrm3951 |
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