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The Mediator complex: a central integrator of transcription

The RNA polymerase II (pol II) enzyme transcribes all protein-coding and most non-coding RNA genes and is globally regulated by Mediator, a large, conformationally flexible protein complex with variable subunit composition (for example, a four-subunit CDK8 module can reversibly associate). These bio...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Nat Rev Mol Cell Biol
Main Authors: Allen, Benjamin L., Taatjes, Dylan J.
Format: Artigo
Jezik:Inglês
Izdano: 2015
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4963239/
https://ncbi.nlm.nih.gov/pubmed/25693131
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nrm3951
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