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A therapeutic nanoparticle vaccine against Trypanosoma cruzi in a BALB/c mouse model of Chagas disease

Chagas disease, caused by Trypanosoma cruzi, results in an acute febrile illness that progresses to chronic chagasic cardiomyopathy in 30% of patients. Current treatments have significant side effects and poor efficacy during the chronic phase; therefore, there is an urgent need for new treatment mo...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Hum Vaccin Immunother
Hauptverfasser: Barry, Meagan A., Wang, Qian, Jones, Kathryn M., Heffernan, Michael J., Buhaya, Munir H., Beaumier, Coreen M., Keegan, Brian P., Zhan, Bin, Dumonteil, Eric, Bottazzi, Maria Elena, Hotez, Peter J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Taylor & Francis 2016
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4962947/
https://ncbi.nlm.nih.gov/pubmed/26890466
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/21645515.2015.1119346
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