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HtrA, a Temperature- and Stationary Phase-Activated Protease Involved in Maturation of a Key Microbial Virulence Determinant, Facilitates Borrelia burgdorferi Infection in Mammalian Hosts

High-temperature requirement protease A (HtrA) represents a family of serine proteases that play important roles in microbial biology. Unlike the genomes of most organisms, that of Borrelia burgdorferi notably encodes a single HtrA gene product, termed BbHtrA. Previous studies identified a few subst...

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Bibliographische Detailangaben
Veröffentlicht in:Infect Immun
Hauptverfasser: Ye, Meiping, Sharma, Kavita, Thakur, Meghna, Smith, Alexis A., Buyuktanir, Ozlem, Xiang, Xuwu, Yang, Xiuli, Promnares, Kamoltip, Lou, Yongliang, Yang, X. Frank, Pal, Utpal
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2016
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4962642/
https://ncbi.nlm.nih.gov/pubmed/27271745
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00360-16
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