Chemically Attenuated Blood-Stage Plasmodium yoelii Parasites Induce Long-Lived and Strain-Transcending Protection

The development of a vaccine is essential for the elimination of malaria. However, despite many years of effort, a successful vaccine has not been achieved. Most subunit vaccine candidates tested in clinical trials have provided limited efficacy, and thus attenuated whole-parasite vaccines are now r...

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Bibliographische Detailangaben
Veröffentlicht in:Infect Immun
Hauptverfasser: Raja, Amber I., Cai, Yeping, Reiman, Jennifer M., Groves, Penny, Chakravarty, Sumana, McPhun, Virginia, Doolan, Denise L., Cockburn, Ian, Hoffman, Stephen L., Stanisic, Danielle I., Good, Michael F.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2016
Schlagworte:
Microbial Immunity and Vaccines
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4962623/
https://ncbi.nlm.nih.gov/pubmed/27245410
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00157-16
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