Tumor Hypoxia Detected by Positron Emission Tomography with (60)Cu-ATSM as a Predictor of Response and Survival in Patients Undergoing Neoadjuvant Chemoradiotherapy for Rectal Carcinoma: A Pilot Study

PURPOSE: The response of rectal cancers to neoadjuvant chemoradiotherapy is variable. Tumor hypoxia reduces the effectiveness of both radiation therapy and chemotherapy and is a well-known risk factor for tumor radioresistence. We hypothesized that imaging with the novel hypoxia-detecting agent, (60...

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Published in:Dis Colon Rectum
Main Authors: Dietz, David W., Dehdashti, Farrokh, Grigsby, Perry W., Malyapa, Robert S., Myerson, Robert J., Picus, Joel, Ritter, Jon, Lewis, Jason S., Welch, Michael J., Siegel, Barry A.
Format: Artigo
Language:Inglês
Published: 2008
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4962601/
https://ncbi.nlm.nih.gov/pubmed/18682881
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10350-008-9420-3
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