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Oncogenic Notch signaling in T and B cell lymphoproliferative disorders
PURPOSE OF REVIEW: Highlight recent discoveries about Notch activation and its oncogenic functions in lymphoid malignancies, and discuss the therapeutic potential of Notch inhibition. RECENT FINDINGS: NOTCH mutations arise in a broad spectrum of lymphoid malignancies and are increasingly scrutinized...
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| 發表在: | Curr Opin Hematol |
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| Main Authors: | , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
2016
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4962559/ https://ncbi.nlm.nih.gov/pubmed/27135981 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/MOH.0000000000000254 |
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