Associations Between Alzheimer Disease Biomarkers, Neurodegeneration, and Cognition in Cognitively Normal Older People

IMPORTANCE: Criteria for preclinical Alzheimer disease (AD) propose β-amyloid (Aβ) plaques to initiate neurodegeneration within AD-affected regions. However, some cognitively normal older individuals harbor neural injury similar to patients with AD, without concurrent Aβ burden. Such findings challe...

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Publicado en:JAMA Neurol
Autores principales: Wirth, Miranka, Villeneuve, Sylvia, Haase, Claudia M., Madison, Cindee M., Oh, Hwamee, Landau, Susan M., Rabinovici, Gil D., Jagust, William J.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2013
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4962545/
https://ncbi.nlm.nih.gov/pubmed/24166579
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1001/jamaneurol.2013.4013
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