Distinct emphysema subtypes defined by quantitative CT analysis are associated with specific pulmonary matrix metalloproteinases

BACKGROUND: Emphysema is characterised by distinct pathological sub-types, but little is known about the divergent underlying aetiology. Matrix-metalloproteinases (MMPs) are proteolytic enzymes that can degrade the extracellular matrix and have been identified as potentially important in the develop...

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Détails bibliographiques
Publié dans:Respir Res
Auteurs principaux: Ostridge, Kristoffer, Williams, Nicholas, Kim, Viktoriya, Harden, Stephen, Bourne, Simon, Coombs, Ngaire A., Elkington, Paul T., Estepar, Raul San Jose, Washko, George, Staples, Karl J., Wilkinson, Tom M. A.
Format: Artigo
Langue:Inglês
Publié: BioMed Central 2016
Sujets:
Research
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4962504/
https://ncbi.nlm.nih.gov/pubmed/27460105
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12931-016-0402-z
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