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Oncolytic virus-mediated targeting of PGE(2) in the tumor alters the immune status and sensitizes established and resistant tumors to immunotherapy

Immunotherapies are highly promising cancer treatments, but understanding the factors mediating their resistance remains critical. Successes in randomized clinical testing have supported the growing appreciation that oncolytic virotherapies primarily act as immunotherapies. Here we identified prosta...

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Detalhes bibliográficos
Publicado no:Cancer Cell
Principais autores: Hou, Weizhou, Sampath, Padma, Rojas, Juan J, Thorne, Steve H
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4962335/
https://ncbi.nlm.nih.gov/pubmed/27374223
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ccell.2016.05.012
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