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2,4,6-Tribromophenol Interferes with the Thyroid Hormone System by Regulating Thyroid Hormones and the Responsible Genes in Mice

2,4,6-Tribromophenol (TBP) is a brominated flame retardant (BFR). Based on its affinity for transthyretin, TBP could compete with endogenous thyroid hormone. In this study, the effects of TBP on the thyroid hormone system were assessed in mice. Briefly, animals were exposed to 40 and 250 mg/kg TBP....

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Détails bibliographiques
Publié dans:Int J Environ Res Public Health
Auteurs principaux: Lee, Dongoh, Ahn, Changhwan, Hong, Eui-Ju, An, Beum-Soo, Hyun, Sang-Hwan, Choi, Kyung-Chul, Jeung, Eui-Bae
Format: Artigo
Langue:Inglês
Publié: MDPI 2016
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4962238/
https://ncbi.nlm.nih.gov/pubmed/27420076
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijerph13070697
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