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Galangin Induces Autophagy via Deacetylation of LC3 by SIRT1 in HepG2 Cells
Galangin suppresses proliferation and induces apoptosis and autophagy in hepatocellular carcinoma (HCC) cells, but the precise mechanism is not clear. In this study, we demonstrated that galangin induced autophagy, enhanced the binding of SIRT1-LC3 and reduced the acetylation of endogenous LC3 in He...
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| Udgivet i: | Sci Rep |
|---|---|
| Main Authors: | , , , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Nature Publishing Group
2016
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4962058/ https://ncbi.nlm.nih.gov/pubmed/27460655 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep30496 |
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