Anticancer Effect of Fucoidan on DU-145 Prostate Cancer Cells through Inhibition of PI3K/Akt and MAPK Pathway Expression

In this study, we showed that PI3K/Akt signaling mediates fucoidan’s anticancer effects on prostate cancer cells, including suppression of proliferation. Fucoidan significantly decreased viability of DU-145 cancer cells in a concentration-dependent manner as shown by MTT [3-(4,5-dimethylthiazol-2-yl...

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Detalhes bibliográficos
Publicado no:Mar Drugs
Main Authors: Choo, Gang-Sik, Lee, Hae-Nim, Shin, Seong-Ah, Kim, Hyeong-Jin, Jung, Ji-Youn
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4962016/
https://ncbi.nlm.nih.gov/pubmed/27399727
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/md14070126
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