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Stationary-Phase Mutagenesis in Stressed Bacillus subtilis Cells Operates by Mfd-Dependent Mutagenic Pathways

In replication-limited cells of Bacillus subtilis, Mfd is mutagenic at highly transcribed regions, even in the absence of bulky DNA lesions. However, the mechanism leading to increased mutagenesis through Mfd remains currently unknown. Here, we report that Mfd may promote mutagenesis in nutritionall...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Genes (Basel)
Hauptverfasser: Gómez-Marroquín, Martha, Martin, Holly A., Pepper, Amber, Girard, Mary E., Kidman, Amanda A., Vallin, Carmen, Yasbin, Ronald E., Pedraza-Reyes, Mario, Robleto, Eduardo A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: MDPI 2016
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4962003/
https://ncbi.nlm.nih.gov/pubmed/27399782
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/genes7070033
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