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Inhibition of TLR4 Signalling-Induced Inflammation Attenuates Secondary Injury after Diffuse Axonal Injury in Rats

Increasing evidence suggests that secondary injury after diffuse axonal injury (DAI) damages more axons than the initial insult, but the underlying mechanisms of this phenomenon are not fully understood. Recent studies show that toll-like receptor 4 (TLR4) plays a critical role in promoting adaptive...

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Vydáno v:Mediators Inflamm
Hlavní autoři: Zhao, Yonglin, Zhao, Yahui, Zhang, Ming, Zhao, Junjie, Ma, Xudong, Huang, Tingqin, Pang, Honggang, Li, Jiaxi, Song, Jinning
Médium: Artigo
Jazyk:Inglês
Vydáno: Hindawi Publishing Corporation 2016
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4961816/
https://ncbi.nlm.nih.gov/pubmed/27478307
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2016/4706915
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