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The Phospholipid:Diacylglycerol Acyltransferase Lro1 Is Responsible for Hepatitis C Virus Core-Induced Lipid Droplet Formation in a Yeast Model System

Chronic infection with the hepatitis C virus frequently induces steatosis, which is a significant risk factor for liver pathogenesis. Steatosis is characterized by the accumulation of lipid droplets in hepatocytes. The structural protein core of the virus induces lipid droplet formation and localize...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:PLoS One
Hauptverfasser: Iwasa, Shingo, Sato, Naoko, Wang, Chao-Wen, Cheng, Yun-Hsin, Irokawa, Hayato, Hwang, Gi-Wook, Naganuma, Akira, Kuge, Shusuke
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2016
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4961368/
https://ncbi.nlm.nih.gov/pubmed/27459103
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0159324
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