Pathological relationships involving iron and myelin may constitute a shared mechanism linking various rare and common brain diseases

We previously demonstrated elevated brain iron levels in myelinated structures and associated cells in a hemochromatosis Hfe(−/−)xTfr2(mut) mouse model. This was accompanied by altered expression of a group of myelin-related genes, including a suite of genes causatively linked to the rare disease fa...

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Publicado no:Rare Dis
Main Authors: Heidari, Moones, Gerami, Sam H., Bassett, Brianna, Graham, Ross M., Chua, Anita C.G., Aryal, Ritambhara, House, Michael J., Collingwood, Joanna F., Bettencourt, Conceição, Houlden, Henry, Ryten, Mina, Olynyk, John K., Trinder, Debbie, Johnstone, Daniel M., Milward, Elizabeth A.
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4961263/
https://ncbi.nlm.nih.gov/pubmed/27500074
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/21675511.2016.1198458
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