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Assessing the utility of intermediate phenotypes for genetic mapping of psychiatric disease

Intermediate phenotypes are traits positioned somewhere between genetic variation and disease. They represent a target for attempts to find disease-associated genetic variants and elucidation of mechanisms. Psychiatry has been particularly enamored with intermediate phenotypes, due to uncertainty ab...

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Bibliographic Details
Published in:Trends Neurosci
Main Authors: Flint, Jonathan, Timpson, Nicholas, Munafò, Marcus
Format: Artigo
Language:Inglês
Published: 2014
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4961231/
https://ncbi.nlm.nih.gov/pubmed/25216981
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tins.2014.08.007
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