CD95-Mediated Calcium Signaling Promotes T Helper 17 Trafficking to Inflamed Organs in Lupus-Prone Mice

CD95 ligand (CD95L) is expressed by immune cells and triggers apoptotic death. Metalloprotease-cleaved CD95L (cl-CD95L) is released into the bloodstream but does not trigger apoptotic signaling. Hence, the pathophysiological role of cl-CD95L remains unclear. We observed that skin-derived endothelial...

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Gepubliceerd in:Immunity
Hoofdauteurs: Poissonnier, Amanda, Sanséau, Doriane, Le Gallo, Matthieu, Malleter, Marine, Levoin, Nicolas, Viel, Roselyne, Morere, Lucie, Penna, Aubin, Blanco, Patrick, Dupuy, Alain, Poizeau, Florence, Fautrel, Alain, Seneschal, Julien, Jouan, Florence, Ritz, Jerome, Forcade, Edouard, Rioux, Nathalie, Contin-Bordes, Cécile, Ducret, Thomas, Vacher, Anne-Marie, Barrow, Paul A., Flynn, Robin J., Vacher, Pierre, Legembre, Patrick
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Cell Press 2016
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4961226/
https://ncbi.nlm.nih.gov/pubmed/27438772
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.immuni.2016.06.028
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