Dendrimer-RNA nanoparticles generate protective immunity against lethal Ebola, H1N1 influenza, and Toxoplasma gondii challenges with a single dose

Vaccines have had broad medical impact, but existing vaccine technologies and production methods are limited in their ability to respond rapidly to evolving and emerging pathogens, or sudden outbreaks. Here, we develop a rapid-response, fully synthetic, single-dose, adjuvant-free dendrimer nanoparti...

詳細記述

保存先:
書誌詳細
出版年:Proc Natl Acad Sci U S A
主要な著者: Chahal, Jasdave S., Khan, Omar F., Cooper, Christopher L., McPartlan, Justine S., Tsosie, Jonathan K., Tilley, Lucas D., Sidik, Saima M., Lourido, Sebastian, Langer, Robert, Bavari, Sina, Ploegh, Hidde L., Anderson, Daniel G.
フォーマット: Artigo
言語:Inglês
出版事項: National Academy of Sciences 2016
主題:
PNAS Plus
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4961123/
https://ncbi.nlm.nih.gov/pubmed/27382155
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1600299113
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