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Generalized nucleation and looping model for epigenetic memory of histone modifications

Histone modifications can redistribute along the genome in a sequence-independent manner, giving rise to chromatin position effects and epigenetic memory. The underlying mechanisms shape the endogenous chromatin landscape and determine its response to ectopically targeted histone modifiers. Here, we...

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Pubblicato in:Proc Natl Acad Sci U S A
Autori principali: Erdel, Fabian, Greene, Eric C.
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2016
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4961120/
https://ncbi.nlm.nih.gov/pubmed/27382173
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1605862113
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