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Media matters: Modeling the impact of solid media performance on tuberculosis trial sample size requirements

SETTING: Two-month solid media culture conversion is a commonly used (if suboptimal) endpoint for phase 2 tuberculosis treatment trials. OBJECTIVE AND DESIGN: To model the effect of solid media performance characteristics (sensitivity and contamination rate) on required sample size for a two-arm cli...

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Detalhes bibliográficos
Publicado no:Int J Tuberc Lung Dis
Main Authors: Johnson, Matthew G., Stout, Jason E., Benator, Debra A., Whitworth, William C., Holland, David P.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4960979/
https://ncbi.nlm.nih.gov/pubmed/27084812
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.5588/ijtld.15.0570
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