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Predictive value of vrk 1 and 2 for rectal adenocarcinoma response to neoadjuvant chemoradiation therapy: a retrospective observational cohort study

BACKGROUND: Neoadjuvant chemoradiotherapy (NACRT) followed by surgical resection is the standard therapy for locally advanced rectal cancer. However, tumor response following NACRT varies, ranging from pathologic complete response to disease progression. We evaluated the kinases VRK1 and VRK2, which...

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Detalhes bibliográficos
Publicado no:BMC Cancer
Main Authors: del Puerto-Nevado, Laura, Marin-Arango, Juan Pablo, Fernandez-Aceñero, Maria Jesus, Arroyo-Manzano, David, Martinez-Useros, Javier, Borrero-Palacios, Aurea, Rodriguez-Remirez, Maria, Cebrian, Arancha, Gomez del Pulgar, Teresa, Cruz-Ramos, Marlid, Carames, Cristina, Lopez-Botet, Begoña, Garcia-Foncillas, Jesús
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4960836/
https://ncbi.nlm.nih.gov/pubmed/27456229
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-016-2574-9
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